Tylenol Avoid or Not to Avoid? Acetaminophen (Tylenol) can deplete glutathione, your body's most important detox antioxidant. This matters even more if your child has an MTHFR gene mutation, which Tylenol, Autism, And The Glutathione Connection OC Integrative Medicine Acetaminophen Toxicity Poisoning sagesteele @P_McCulloughMD While I dont know whether there is a connection between Tylenol and autism, I do believe that there is reason to STOP giving it to babies children. Glutathione is impacted by Tylenol, Glutathione, Metals, and Folate Pathways: What Actually Helps Our Kids The Acetaminophen Molecule Tylenol