A biological miracle is happening in anti aging where the body takes out the trash. The peptide reduced frailty markers by 50% in aged mice, inducing apoptosis (death) only in damaged cells. It FOXO4 DRI: The Senolytic Peptide That Targets Zombie Cells and Aging Revolution Health & Wellness The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv 2022 Lupus Highlight Therapeutic Targeting of Senescent Cells in Lupus, Lupus Research Program, Congressionally Directed Medical Research Programs FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect