Glutathione Therapy Specialist in Orlando, FL Glutathione IV Therapy: Timeline for Skin Lightening Oral glutathione has been everyone on my timeline but does it actually work?! Looking at the data, its very modest to be honest. Id recommend sticking to what we know works fo hyperpigmentation in What Is Glutathione? Health Benefits, Risks, and More Will IV glutathione work for everyone? , With almost 10 years of experience, my answer is no. The results of IV glutathione vary depending on , 1) what outcome we are using it for ( doesnt work for Glutathione: Benefits and Supplements