Chronic Desensitization and Down regulation of the Gastrin releasing Peptide Receptor Are Mediated by a Protein Kinase C dependent Mechanism ScienceDirect Insulin Resistance: From Mechanisms to Therapeutic Strategies The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline Frontiers Biased Signaling of Protease Activated Receptors Everyone talks about the glow from GHK Cu Nobody talks about the burn. Yes, GHK Cu gets hyped for tighter looking skin, scar support, collagen support, and regeneration. And the reason people talk about it Conformational restriction blocks glutamate receptor desensitization Nature Structural & Molecular Biology