Early life acetaminophen exposure, glutathione S transferase genes, and development of adolescent asthma in a high risk birth cohort Journal of Allergy and Clinical Immunology Taking Tylenol? The Glutathione Connection Dr. Green Mom Tylenol's Impact on Glutathione and Liver Damage Tylenol's Impact on Glutathione and Liver Damage Yes there is good evidence that acetaminophen (the active ingredient in Tylenol) can deplete glutathione under certain conditions. But whether that matters depends on dose, duration, and individual factors. How to Fix Glutathione from Tyleon TikTok