Oral melanoma and other pigmentations: when to biopsy? Lambertini 2018 Journal of the European Academy of Dermatology and Venereology Wiley Online Library Oral Melanotic Macule MEDizzy Labial melanotic macule a Multifocal brown macules on the hard palate showing variation in Download Scientific Diagram Metastatic oral malignant melanoma transformed from pre existing pigmented lesions in mandibular gingiva: Report of an unusual case ScienceDirect Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.