Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 PDF] Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis. Semantic Scholar Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Oral Melanotic Macule: Symptoms and Treatment Skinsight Labial Melanotic Macules DoveMed Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update