3 Different Types of B12 MedClub by Dr Jenn Methylcobalamin vs Cyanocobalamin: What's the Difference? B12 Methylcobalamin vs Hydroxocobalamin The difference between in clinic B12 injections vs over the counter. There are many forms of vitamin B12, the form used at La Bella is Methylcobalamin. The Cyanocobalamin vs Hydroxocobalamin (Vitamin B12 forms) Key Clinical Differences Hydroxocobalamin is preferred in: Pernicious anemia Severe vitamin B12 deficiency Neurological symptoms (subacute combined degeneration, neuropathy) Cyanocobalamin is Cyanocobalamin (B12) 1000mcg mL Injection 30mL MDV McGuff Cyanocobalamin vs. Methylcobalamin: Unraveling the Differences and Benefits Brandon Medical Center