Oral Melanotic Macule: Symptoms and Treatment Skinsight Labial Melanotic Macules DoveMed Melanotic macules of the tongue in a newborn Journal of the American Academy of Dermatology Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in