Glucose 6 phosphate dehydrogenase deficiency The Lancet Figure 2 from Impact of glucose 6 phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease. Semantic Scholar Glucose 6 phosphate dehydrogenase deficiency pathophysiology wikidoc JaypeeDigital eBook Reader Glucose 6 phosphate dehydrogenase (G6PD) deficiency G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No