Methyl Group Metabolism in Differentiation, Aging, and Cancer When people think about detox, they usually think about the liver. But detoxification actually involves several systems working together. One of the most important is methylation. Methylation supports processes involved in Frontiers Regulation of epigenetic traits of the glutathione S transferase P1 gene: from detoxification toward cancer prevention and diagnosis Methylation as a key regulator of Tau aggregation and neuronal health in Alzheimer's disease Cell Communication and Signaling Springer Nature Link Glutathione Synthesis Explained: How Your Body Builds Its Master Antioxidant OrganiClinic Homocysteine: The Hidden Risk Factor Many Doctors Miss The School of Applied Functional Medicine