Arsenicglutathione conjugate transport by the human multidrug resistance proteins (MRPs ABCCs) ScienceDirect Arsenic, lead, and mercury are ranked the top three environmental toxins on the EPA priority list. They affect the nervous system, immune system, cardiovascular system, and endocrine system. Yet in conventional medicine, Glutathione Is Involved in the Reduction of Methylarsenate to Generate Antibiotic Methylarsenite in Enterobacter sp. Strain CZ 1 Applied and Environmental Microbiology Glutathione depletion overcomes resistance to arsenic trioxide in arsenic resistant cell lines Leukemia Nrf2 activation ameliorates cytotoxic effects of arsenic trioxide in acute promyelocytic leukemia cells through increased glutathione levels and arsenic efflux from cells ScienceDirect The SLIM1 transcription factor is required for arsenic resistance in Arabidopsis thaliana bioRxiv