Can You Donate Blood if You Smoke Weed? It's Complicated Weedmaps Can you smoke when As e cigarette use grows, more research needed on long term effects of vaping American Heart Association We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating Does Vaping Cause Lung Cancer? INTEGRIS Health Smoking (or vaping) doesn't affect your ability to donate blood. Help us bust this myth by sharing our post.