Do Vapes Set off Smoke Alarms? Does Vape Trigger Smoke Detectors Can Vape Trigger Smoke Alarm Can Vaping Set Off A Smoke Think vapes are harmless to your smoke alarms? Not always. Vapor clouds from ecigarettes can drift into smoke alarms and trigger false alarms, especially in smaller rooms. Even lighter vapes can News will vape set off smoke alarm Can Vape Pens Trigger Smoke Alarms in Buildings or Planes? How Vape Detectors and Sensors Work: An Informative Guide