Small molecule activation of the neurotrophin hepatocyte growth factor to treat Alzheimer disease Role of the HGF c MET tyrosine kinase inhibitors in metastasic melanoma Molecular Cancer Springer Nature Link Recent advances in the discovery of small molecule c Met Kinase inhibitors ScienceDirect Mechanistically detailed systems biology modeling of the HGF Met pathway in hepatocellular carcinoma npj Systems Biology and Applications Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted HGF c Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR NGF axis Cell Death & Disease
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