Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black G6PD Deficiency causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione ( Frontiers The global role of G6PD in infection and immunity Pathology of G6PD deficiency Pathology Made Simple PeerJ The research progress on the role of glucose 6 phosphate dehydrogenase in immune regulation G 6 PD OSMMR2000 instructions