A Possible Antidote for Tylenol (Paracetamol) Overdose American Council on Science and Health Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors sagesteele @P_McCulloughMD While I dont know whether there is a connection between Tylenol and autism, I do believe that there is reason to STOP giving it to babies children. Glutathione is impacted by Yes there is good evidence that acetaminophen (the active ingredient in Tylenol) can deplete glutathione under certain conditions. But whether that matters depends on dose, duration, and individual factors. Tylenol And Glutathione Invigor Medical Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health